Peptides Everywhere
Essjay@essjay
+1.1%
since Oct 14
The idea
I believe peptide medicines are about to go from one blockbuster drug class to the default way we treat dozens of conditions, as routine as vaccines. Rather than pick which drug wins, I own the picks and shovels: equipment and supplies that make and purify peptides, split evenly with the pens, syringes and delivery tech that get them into patients, plus a smaller slice of biotechs exploring peptides beyond weight loss, each kept small since one failed trial can hurt a single name badly.
What it owns
- Most peptides are still injected, so makers of pens, needles, glass cartridges and delivery technology benefit as more peptide drugs reach patients. · West Pharmaceutical ServicesIt makes the rubber plungers, stoppers and seals inside the pens and vials that hold injectable drugs, so pen injection volume drives its component sales., Becton, Dickinson and CompanyIt makes syringes and injection devices by the billions, so if peptide shots become routine like vaccines, large volume runs through its devices business., Halozyme TherapeuticsIts technology lets drugs be injected under the skin instead of through an IV and makes autoinjectors, keeping its licensing deals with drugmakers active., EmbectaIt specializes in pen needles, the disposable needle used with nearly every pen injection, with volumes rising as more peptides are delivered by pen., InsuletIt makes the Omnipod, a wearable pump for insulin which is a peptide hormone, and wearable delivery could expand to other peptides over time.32%
- Every new peptide requires synthesis, purification and testing equipment, so these suppliers sell to all companies making peptide drugs regardless of which one wins. · Thermo Fisher ScientificIt sells the equipment and supplies peptide factories use and makes drugs under contract, so its revenue grows as drugmakers add peptide production capacity., DanaherIts Cytiva unit sells the filters, resins and purification equipment used to clean up peptides after they are made during large-scale production., Waters CorporationIt makes the testing instruments that verify every batch of peptide drug for purity before shipment, with demand rising as peptide production scales up., Agilent TechnologiesIt sells chromatography columns and instruments used to separate and test peptides during manufacturing, with pharma sales growing alongside peptide volumes., AvantorIt supplies the high-purity solvents, chemicals and resins used every time a peptide is made, with bioprocessing sales growing as peptide volumes rise.31%
- Small companies are proving peptides work for psoriasis, blood disorders, rare hormone diseases and cancer, showing how peptides spread across many different uses. · Protagonist TherapeuticsIts icotrokinra was approved as a psoriasis pill, showing peptides now reach diseases beyond injection and weight loss through pill-based delivery., Rhythm PharmaceuticalsIts setmelanotide is a peptide for rare genetic hunger and obesity disorders, proving peptides treat uses well outside mainstream weight loss., Ascendis PharmaIt makes long-lasting versions of hormone peptides so patients dose far less often, with hormone products selling and the pipeline advancing., Xeris BiopharmaIt makes ready-to-inject, room-temperature drug formulations including its glucagon rescue pen and licenses that technology to other peptide companies., Perspective TherapeuticsIt uses peptides to carry radiation straight to tumors, extending the peptide idea into cancer treatment through a novel delivery mechanism.14%
- Companies that produce peptide drugs themselves, including cheaper generic versions as patents expire, capture the margin from manufacturing at scale. · Amphastar PharmaceuticalsIt makes peptide drugs itself, including glucagon treatments and other injectables, in its own plants with peptides as a growing share of output., Teva Pharmaceutical IndustriesIt makes generic copies of drugs including peptides, so as older peptide drugs lose patent protection it can produce them at scale.8%
- Cash15%